Article
Familial Aggregation of Parkinson Disease and Essential Tremor in Early and Late Onset Parkinson Disease Cohorts.
Neurology - 28 Jul 2026
Malfer Lorenzo, Liu Tina, Mullan Aidan, Santoro Emanuela, Lynott Elena B, Troxel Colton E, Derhab Mohamed, Ghoniem Khaled, Ross Owen A, Bower James H, Savica Rodolfo
Abstract excerpt
OBJECTIVES: Early-onset Parkinson disease (EOPD) is associated with stronger genetic contributions than late-onset Parkinson disease (LOPD). However, the complex interplay between genetic susceptibility, family history, and environmental factors remains incompletely understood. This study assesses familial aggregation of PD and essential tremor (ET) among relatives of patients with EOPD and compares it with...
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