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Ralstonia pseudosolanacearum PhcQ Controls Quorum Sensing-Dependent Phenotypes by Binding PhcA and Maintaining Its Protein Stability.

Molecular plant pathology - 1 Jul 2026

Chen Min, Luo Lili, Yang Huixin, Hu Liujie, Liang Tao, Tsuzuki Masayuki, Hikichi Yasufumi, Ohnishi Kouhei, Guo Tao, Li Chengtao, Li Peng, Zhang Yong

Abstract excerpt

The quorum-sensing (QS) system plays a crucial role in regulating the virulence of the Ralstonia solanacearum species complex (RSSC). It is controlled by the phcBSR operon and phcA genes. PhcQ may contribute to the activation of PhcA and regulates the expression of QS-dependent genes. Here, we genetically demonstrate that PhcQ functions as a key component of the QS regulatory pathway by maintaining the protein...

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PMID: 42383340
DOI: 10.1111/mpp.70308
PMCID: PMC13320629

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