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Article

Genomic and transcriptomic analysis suggests potential regulatory relationships among MC1R, TUBB3, and PMEL associated with black-flecked plumage in chickens.

BMC genomics - 29 Jun 2026

Guo Yifan, Chen Yuqi, Guo Huanjie, Wang Binghui, Gong Yanzhang, Li Jingyi

Abstract excerpt

The Dominant white (I) allele in chickens suppresses the expression of black eumelanin, resulting in white plumage. However, both previous reports and our observations showed that some heterozygous (I/i+) individuals exhibited black-flecked plumage rather than completely white plumage, unlike homozygous dominant white chickens. This phenomenon suggests incomplete penetrance and incomplete dominance of the I...

Read the complete abstract on PubMed

Topics

Animals
Chickens
Feathers
Receptor, Melanocortin, Type 1
Genomics
Gene Expression Profiling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Pigmentation

Phenotype

Tubulin

Melanins

Melanogenesis

Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 42374170
DOI: 10.1186/s12864-026-13107-w
PMCID: PMC13584571

Genes

MC1R
PMEL
TUBB3

Variants

Provenance

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