Agentic Artificial Intelligence-Driven Explainable Deep Learning for Deciphering Noncoding Pathogenic Mechanisms of Delirium Through Genomic Big Data Integration.

Abstract excerpt

Delirium is a prevalent neuropsychiatric syndrome affecting up to 50% of hospitalized elderly patients, associated with increased mortality, cognitive decline, and health care costs exceeding $164 billion annually. Despite its clinical burden, the genetic architecture underlying susceptibility to delirium remains poorly characterized. We developed an agentic artificial intelligence pipeline integrating...

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