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Article

Genetic evidence that advanced COVID-19 accelerates longitudinal brain atrophy: A Mendelian randomization study.

Medicine - 26 Jun 2026

Wen Jie, Chen Yuyao, Zhang Jingwei, Tan Zeming, Xia Zhiwei, Yang Sisi, Liu Hongwei

Abstract excerpt

Coronavirus disease 2019 (COVID-19) was reported to persist long-term in the brain and leave several long-term neurologic sequelae. However, the causal relationship between COVID-19 and brain aging is still unknown. The genome-wide association study (GWAS) data on COVID-19 phenotypes (susceptibility, hospitalization, and severity), involving a total of 5,779,391 participants, were collected from the COVID-19 Host...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42363551
DOI: 10.1097/MD.0000000000049310
PMCID: PMC13313741

Genes

CDH15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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