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Article

Association of athlete's heart and ACE I/D genotype with later-life left ventricular hypertrophy: a retrospective cohort study.

BMC cardiovascular disorders - 26 Jun 2026

Someya Yuki, Miyamoto-Mikami Eri, Takaragawa Mizuki, Fuku Noriyuki, Naito Hisashi

Abstract excerpt

BACKGROUND: "Athlete's heart" refers to the physiological cardiac hypertrophy observed in competitive athletes, which reverts to normal after retirement from competition. However, few studies have examined long-term follow-up. This study investigated whether former college athletes with a history of an athlete's heart have a higher risk of developing heart disease later in life and examined its association with...

Read the complete abstract on PubMed

Topics

Humans
Peptidyl-Dipeptidase A
Hypertrophy, Left Ventricular
Male
Athletes
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Retrospective Studies

Phenotype

Japan

Genetic Predisposition to Disease

Risk Factors

Cardiomegaly, Exercise-Induced

Risk Assessment

Adult

Age Factors

Prevalence

Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 42363073
DOI: 10.1186/s12872-026-06171-3
PMCID: PMC13563767

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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