Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training.

doi:10.1161/01.cir.96.3.741

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Article

Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training.

Circulation - 5 Aug 1997

Montgomery H E, Clarkson P, Dollery C M, Prasad K, Losi M A, Hemingway H, Statters D, Jubb M, Girvain M, Varnava A, World M, Deanfield J, Talmud P, McEwan J R, McKenna W J, Humphries S

Abstract excerpt

BACKGROUND: The absence (deletion allele [D]) of a 287-base pair marker in the ACE gene is associated with higher ACE levels than its presence (insertion allele [I]). If renin-angiotensin systems regulate left ventricular (LV) growth, then individuals of DD genotype might show a greater hypertrop...

Topics

Adult
Alleles
Cohort Studies
Echocardiography
Electrocardiography
Genotype
Heart Ventricles
Humans
Hypertrophy, Left Ventricular
Male
Military Medicine
Natriuretic Peptide, Brain
Nerve Tissue Proteins
Peptidyl-Dipeptidase A

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Physical Education and Training

Polymorphism, Genetic

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Identifiers

PMID: 9264477
DOI: 10.1161/01.cir.96.3.741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9264477-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.