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Host-pathogen interplay of Orientia tsutsugamushi: pathomolecular epidemiology and phylo-immuno profiling in naturally infected rodents and shrews.

Microbial pathogenesis - 1 Sept 2026

Mote Akash Balasaheb, Dhanze Himani, Asok Kumar M, Thomas Prasad, Verma Princee, Singh Vibha, Singh Rahul, Gupta Ishita, Kumar M Suman, Singh Rajeev, Ram Hira, Kumar Bablu, Sharma G Taru

Abstract excerpt

Scrub typhus is a notable zoonosis, yet natural host-associated pathogen prevalence and genotypic diversity remain underexplored. A total of 261 small mammals comprising rodents and shrews captured in Uttar Pradesh, India, were screened for Orientia tsutsugamushi (OT) using nested PCR. The sample included Rattus rattus (n = 28), Rattus norvegicus (n = 42), Rattus tanezumi (n = 42), Bandicota bengalensis (n = 10),...

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PMID: 42341958
DOI: 10.1016/j.micpath.2026.108656

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