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Article

Impact of smoking status on Sjögren's disease diagnosis and phenotype: results from a cohort study with matched population controls.

Rheumatology (Oxford, England) - 30 Jun 2026

Bandeira Matilde, Baranskaya Aliaksandra, Pucino Valentina, Nayar Saba, Higham Jon, Poveda-Gallego Ana, Rauz Saaeha, Bowman Simon J, Fisher Benjamin A

Abstract excerpt

OBJECTIVES: To examine associations between smoking and Sjögren's disease (SjD) diagnosis, compared with non-Sjögren's sicca syndrome (sicca) and population controls, and to explore immunomodulatory effects of smoking on disease phenotype. METHODS: Adults referred for suspected SjD to the Optimising Assessment in Sjögren's Syndrome (OASIS) cohort from 2014 until 2023 were classified as SjD or sicca. Smoking...

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Identifiers

PMID: 42340680
DOI: 10.1093/rheumatology/keag334
PMCID: PMC13384511

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