Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Considering Tumour Sidedness is Critical for Accurate Interpretation of Liquid Biopsy Results in Metastatic Colorectal Cancer.

Molecular diagnosis & therapy - 1 Jul 2026

Toledano-Fonseca Marta, de la Fuente Icíar, Ortiz-Morales María José, Cano-Ramírez Pablo, Pulido-Cortijo Gema, Cano-Osuna María Teresa, García-Ortiz María Victoria, Gómez-España María Auxiliadora, Rodríguez-Ariza Antonio, Aranda Enrique

Abstract excerpt

BACKGROUND: Colorectal cancer is one of the most common and deadly malignancies worldwide. Traditionally, all colon tumours have been treated as a single entity, but growing evidence shows that tumour behaviour differs markedly according to tumour sidedness. Right-sided and left-sided tumours exhibit distinct molecular profiles, prognoses and therapeutic responses. A liquid biopsy is a minimally invasive approach...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoembryonic Antigen

Share to Cell-Free Nucleic Acids

Share to Colorectal Neoplasms

Share to Liquid Biopsy

Share to Neoplasm Metastasis

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 42324399
DOI: 10.1007/s40291-026-00856-3
PMCID: PMC13319506

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Considering Tumour Sidedness is Critical for Accurate Interpretation of Liquid Biopsy Results in Metastatic Colorectal Cancer.PMID 42324399Read ↗

Does side matter? Deciphering mechanisms that underpin side-dependent pathogenesis and therapy response in colorectal cancerSemantic proximity Read ↗

Metastatic Bulk Independently Predicts Outcomes for EGFR Precision Targeting in Colorectal Cancer.Semantic proximity Read ↗

Should rectal cancer be regarded as a different tumor entity from left-sided colon cancer? A clinical and molecular NGS-based study of 552 casesSemantic proximity Read ↗

Precision surgery for colorectal liver metastases: Opportunities and challenges of omics-based decision making.Semantic proximity Read ↗

Comprehensive genomic profiling of small bowel adenocarcinoma by tissue and plasma biopsy.Semantic proximity Read ↗

Classifying Colorectal Cancer by Tumor Location Rather than Sidedness Highlights a Continuum in Mutation Profiles and Consensus Molecular SubtypesSemantic proximity Read ↗

Tumor location matters, next generation sequencing mutation profiling of left-sided, rectal, and right-sided colorectal tumors in 552 patients.Semantic proximity Read ↗

The Added Value of Baseline Circulating Tumor DNA Profiling in Patients with Molecularly Hyperselected, Left-sided Metastatic Colorectal Cancer.Semantic proximity Read ↗

The Good, the Bad and the Ugly - Novel Synoptic Variables in the Personalisation of Colon Cancer TreatmentSemantic proximity Read ↗

Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer.Semantic proximity Read ↗

Analysis of Clinicopathological Histomorphological and Molecular Differences in Right and Left Sided Colonic CarcinomaSemantic proximity Read ↗

Colorectal Cancer: Why Does Side Matter?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.