Multimodal phenotypic clustering predicts cardiac outcomes in Fabry disease.

Abstract excerpt

BACKGROUND: Fabry disease (FD) is a rare lysosomal storage disorder with cardiac involvement. The efficacy of cardiac assessments in predicting disease progression is uncertain and few long-term studies have evaluated a clinically comprehensive approach in tracking cardiac outcomes. We developed a multi-modal framework integrating sex, genetics, clinical assessments, electrocardiography (ECG), imaging, and...

Topics

• Humans
• Fabry Disease
• Female
• Male
• Electrocardiography
• Adult
• Middle Aged