Article
Two diseases presenting only as cardiac hypertrophy: differences between the late-onset Fabry disease cardiac variant and hypertrophic cardiomyopathy.
BMC cardiovascular disorders - 4 Feb 2026
Lin Lirong, Liu Jichen, Xie Zhangxin, Yin Lei, Wang Rehua, Huang Shujie, Zhang Dusheng, Chen Wei, Wu Zhiyong, Wang Xiaohu, Zhang Zujie, Zheng Lixian, Lu Nan, Dai Ying, Chen Mingfeng, Guo Yansong, Lu Lihong
Abstract excerpt
BACKGROUND: Cardiac involvement is the leading cause of death in Fabry disease (FD), but the “cardiac variant” is often misdiagnosed as hypertrophic cardiomyopathy (HCM). This study systematically compared late-onset FD cardiac variant and HCM across clinical, electrocardiographic (ECG), echocardiographic and cardiac magnetic resonance (CMR) features to improve diagnostic accuracy. METHODS: The clinical data,...
Topics
- Humans
- Fabry Disease
- Female
- Male
- Cardiomyopathy, Hypertrophic
- Middle Aged
- Electrocardiography
- Adult
- Predictive Value of Tests
- Retrospective Studies