Article
Case Report: Tumor regression and neurological recovery in paraplegia from POLD1-mutated hepatocellular carcinoma treated with targeted immunotherapy and electroacupuncture.
Frontiers in immunology - 1 Jan 2026
Pang Xionghao, Zhao Xinyi, Lin Jiajian, Wang Yansu, Xiao Liang, Li Meixiang, Dong Lin, Xie Yaoguang, Jiang Lingzhi, Yang Caiping, Tian Geng
Abstract excerpt
Background: Hepatocellular carcinoma (HCC) patients with bone metastasis-induced paraplegia have an extremely poor prognosis. The potential for neurological recovery following immunotherapy and subsequent rehabilitation in this population remains unclear. Case: A 58-year-old male with Barcelona Clinic Liver Cancer stage C (BCLC) HCC and T11 vertebral metastasis causing American Spinal Injury Association (ASIA)...
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