Article
Cortical correlates of apathy in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy with two different pathogenic mutations in the NOTCH3 gene.
Neuropsychology - 1 Sept 2026
De Lucia Natascia, Ragno Michele, Cacchiò Gabriella, Papiri Giulio, Maldonato Nelson Mauro, Caulo Massimo, Pianese Luigi, De Michele Giuseppe, Trojano Luigi
Abstract excerpt
OBJECTIVE: Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) patients may frequently manifest apathy. The cognitive and neural mechanisms underlying apathy in CADASIL have not been assessed systematically. The aim was to investigate neuropsychological and brain morphological features associated with apathy in patients with p.R1006C in exon 19 (nucleotide change...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.