Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The GNB3 C825T Polymorphism Is Associated With Decreased Risk of Recurrence of Large-Artery Atherosclerotic Acute Ischemic Stroke.

Journal of the American Heart Association - 16 Jun 2026

Yan Ran, Qiu Xin, Dai Yalun, Yang Kaixuan, Gu Hongqiu, Jiang Yong, Cheng Si, Meng Xia, Wang Yilong, Zhao Xingquan, Li Hao, Wang Yongjun, Li Zixiao

Abstract excerpt

BACKGROUND: GNB3 C825T polymorphism affects G protein-coupled receptor signaling, influencing platelet function, inflammation, and cardiovascular risk. This study aimed to investigate the unknown effects of the GNB3 C825T polymorphism on recurrent stroke risk in large-artery atherosclerosis and its potential interaction with antiplatelet therapy. METHODS: Using the CNSR-III (Third China National Stroke Registry)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspirin
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Ischemia

Share to Heterotrimeric GTP-Binding Proteins

Share to Intracranial Arteriosclerosis

Share to Ischemic Stroke

Share to Platelet Aggregation Inhibitors

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 42294757
DOI: 10.1161/JAHA.125.047271
PMCID: PMC13323571

Genes

GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The GNB3 C825T Polymorphism Is Associated With Decreased Risk of Recurrence of Large-Artery Atherosclerotic Acute Ischemic Stroke.PMID 42294757Read ↗

The C825T GNB3 polymorphism, independent of blood pressure, predicts cerebrovascular risk at a population level.Semantic proximity Read ↗

Impact of miR-200b and miR-495 variants on the risk of large-artery atherosclerosis stroke.Semantic proximity Read ↗

Association of the Single Nucleotide Polymorphisms in microRNAs 130b, 200b, and 495 with Ischemic Stroke Susceptibility and Post-Stroke Mortality.Semantic proximity Read ↗

Matrix Gla protein polymorphism rs1800801 associates with recurrence of ischemic stroke.Semantic proximity Read ↗

Association between platelet glycoprotein Ia C807T gene polymorphism and ischemic stroke: a meta-analysis in a separate ethnic group.Semantic proximity Read ↗

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke.Semantic proximity Read ↗

Variants on chromosome 9p21.3 correlated with ANRIL expression contribute to stroke risk and recurrence in a large prospective stroke population.Semantic proximity Read ↗

GNB3 gene 825 TT variant predicts hard coronary events in the population-based Heinz Nixdorf Recall study.Semantic proximity Read ↗

Associations Between Gene Variants of Lipid-Lowering Drug Targets and Adverse Outcomes After Ischemic Stroke.Semantic proximity Read ↗

The C825T polymorphism of the G-protein β3 subunit gene and its association with hypertension and stroke: an updated meta-analysis.Semantic proximity Read ↗

Inflammation-Related circRNA Polymorphism and Ischemic Stroke Prognosis.Semantic proximity Read ↗

Genetic variants of platelet glycoprotein receptors and risk of stroke in young women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.