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Article

Association of apolipoprotein E polymorphisms (E2, E3, E4) with type 2 diabetes: a meta-analysis of case-control studies.

The Pan African medical journal - 1 Jan 2026

Zouine Chaimae, Ikhanjal Mohamed Amine, Errafii Khaoula, Charoute Hicham, Es-Saadi Meriem, Benhnini Fouad, Messoudi Nouha, Ghazi Bouchra, Hamdi Salsabil

Abstract excerpt

Type 2 diabetes (T2D) accounts for over 90% of all diabetes cases and results from the interaction of genetic and environmental factors. However, the association between apolipoprotein E (APOE) gene polymorphisms and T2D risk shows considerable variation across different populations. This meta-analysis aims to clarify the association between APOE genotypes and alleles (E2E2, E2E3, E2E4, E3E4, E4E4) and the risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Diabetes Mellitus, Type 2

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 42283046
DOI: 10.11604/pamj.2026.53.48.45564
PMCID: PMC13252076

Genes

APOE
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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