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Article

Early insights into donor-derived cell-free DNA in a preclinical model of face vascularized composite allotransplantation.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS - 1 Aug 2026

Noel Olivier F, Gonzalez Luis, Xu Yiting, Carter Kristyn, Huelsboemer Lioba, Stogner Viola, Williams Mica, Horsley Valerie, Pomahac Bohdan

Abstract excerpt

BACKGROUND: Acute rejection remains a major challenge following face vascularized composite allotransplantation (VCA) and can lead to allograft dysfunction or loss. Donor-derived cell-free DNA (ddcfDNA) has emerged as a promising noninvasive biomarker for allograft injury and rejection monitoring in solid organ transplantation. However, its application to VCA remains largely unexplored, and data characterizing...

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PMID: 42275695
DOI: 10.1016/j.bjps.2026.05.069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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