Article
HMGA2 identified via m6A-senescence multi-omics in laryngeal squamous cell carcinoma.
Scientific reports - 9 Jun 2026
Jin Meng, Qu Lingmei, Xu Zhaonan, Teng Shuang, Liu Shuo, Li Qiuying, Zhang Fengshuo, Hao Qing, Wang Peng, Zhao Rui, Yan Bingrui, Sun Yanan
Abstract excerpt
N6-methyladenosine (m6A) modification and cellular senescence have been individually implicated in tumor biology, but the landscape of m6A-related senescence genes in laryngeal squamous cell carcinoma (LSCC) remains underexplored. In this study, we conducted an integrated multi-omics analysis combining bulk and single-cell transcriptomics, somatic mutation and copy number variation data, and proteomics to explore...
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