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Article

Mannose Receptor C Type 2 Predicts Poor Outcome in Glioma and is Associated With Invasive Phenotypes and β-Catenin/EMT-related Changes.

Journal of visualized experiments : JoVE - 19 May 2026

Yu Yanni, Ji Lijing, Li Juan, Tian Yu, Wang Zhiwen, Tu Yanyang, Zhen Haining, Xu Lei

Abstract excerpt

Glioma remains a lethal malignancy of the central nervous system, and additional biomarkers that improve prognostic stratification and inform therapeutic exploration are still needed. This study evaluated mannose receptor C-type 2 (MRC2/Endo180) by integrating public transcriptomic cohorts with in vitro validation. Expression profiles and matched clinical annotations were obtained from The Cancer Genome Atlas...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42258494
DOI: 10.3791/70882

Genes

MRC2
CDK4
CDK6
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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