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Article

Retrospective Analysis of HER2 Testing, Treatment Patterns, and Clinical Outcomes in Patients With Locally Advanced or Metastatic NSCLC With HER2 Mutations in France.

Cancer medicine - 1 Jun 2026

Debieuvre Didier, Macouillard Pauline, Quantin Xavier, Berktas Mehmet, Girard Nicolas, Audigier-Valette Clarisse, Filleron Thomas, Musilli Stefania, Bosquet Lise, Pérol Maurice

Abstract excerpt

BACKGROUND: HER2 (ERBB2) gene mutations are associated with poor prognosis in non-small cell lung cancer (NSCLC). It is important to identify patients with HER2-mutant (HER2m) NSCLC, as new targeted treatment options are emerging. However, HER2 testing in clinical practice varies across regions, and real-world data on HER2m NSCLC are limited. PATIENTS AND METHODS: This retrospective study included patients from...

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Identifiers

PMID: 42252502
DOI: 10.1002/cam4.71975
PMCID: PMC13243172

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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