Article
Genomic and proteogenomic insights into Spontaneous Coronary Artery Dissection (SCAD): A systematic review of emerging multi-omic evidence.
Vascular pharmacology - 1 Sept 2026
Russo Alice, Alberti Mattia, Biondi Filippo, Aquaro Giovanni Donato, Morrone Doralisa, Madonna Rosalinda, De Caterina Raffaele
Abstract excerpt
BACKGROUND: Spontaneous coronary artery dissection (SCAD) is a major cause of myocardial infarction in young women without traditional cardiovascular risk factors (Hayes et al., 2018; Adlam et al., 2018 [1, 2]). Despite growing awareness, its biological underpinnings remain incompletely understood, and clinical management is largely based on observational evidence rather than mechanistic insight (Saw et al.,...
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- Animals
- Humans
- Coronary Vessel Anomalies
- Dissection, Blood Vessel
- Epitranscriptomics
- Genetic Predisposition to Disease