The DENN Protein SMD1 Forms a Signalling Hub With Rab GTPase YPT1 to Regulate Diverse Biological Processes in Phytopathogenic Fungi and Serves as a HIGS Target for Crop Protection.

Abstract excerpt

Sclerotinia sclerotiorum is a notorious necrotrophic plant pathogen that causes severe yield losses in many important crops. Despite its profound economic impact, the molecular mechanisms underpinning its development and virulence processes remain largely elusive. In this study, we characterized a mutant with reduced virulence through a forward genetic screen. Genetic analysis confirmed that mutations in a gene...

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