Genetics and Primary Aldosteronism: Disease Phenotype and Demographic Implications for Hypertension.

Abstract excerpt

Detecting secondary forms of hypertension is key to targeted management and prevention of cardiovascular complications. Primary aldosteronism (PA) is the most common form of secondary arterial hypertension, resulting from excess adrenal unilateral or bilateral aldosterone production. Its prevalence rises with hypertension severity, reaching 25% in treatment-resistant patients. Understanding the genetic basis of...

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