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Article

Canalization of neural dynamics by δ-protocadherins in the developing zebrafish optic tectum.

PLoS genetics - 1 Jun 2026

Biswas Sayantanee, Emond Michelle R, Philip Grace S, Jontes James D

Abstract excerpt

Brain dynamics are constrained by the underlying topology of neuronal networks. How genes collaborate to organize these neural networks during development remains an enduring mystery. In humans, large numbers of genes have been implicated in neurodevelopmental disorders that are characterized by variable and overlapping phenotypes. The complexity of the brain and the heterogeneity of the disorders makes...

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PMID: 42224358
DOI: 10.1371/journal.pgen.1012171
PMCID: PMC13241009

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