Phenotype-driven protocol switching is associated with improved ART outcomes under constant gonadotropin dosage: a self-controlled analysis of 4,632 cycles.

Abstract excerpt

Background: Managing failure after an initial assisted reproductive technology (ART) cycle remains a significant clinical challenge. Clinicians often face a dilemma between repeating the index protocol, escalating gonadotropin (Gn) dosages, or switching to an alternative strategy. We aimed to evaluate whether phenotype-driven protocol switching, specifically addressing issues like over-suppression or poor embryo...

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