Article
The FAP-FDG Integration Score (FFIS): Development and prognostic validation of a dual-tracer PET phenotype for solid tumors.
European journal of nuclear medicine and molecular imaging - 1 Jul 2026
Liu Ya, Zhang Ting, Deng Jingwei, Yu Chang, Xu Tingting, Mou Lixian, Ding Haoyuan, Chen Yue
Abstract excerpt
PURPOSE: To develop a FAP-FDG integrated score (FFIS) based on [68Ga]Ga-FAP-2286 and [18F]F-FDG PET/CT, and evaluate its prognostic value for risk stratification compared to conventional single-parameter imaging. METHODS: This retrospective study included 193 patients with solid tumors who underwent both [18F]F-FDG and [68Ga]Ga-FAP-2286 PET/CT scans. Overall survival (OS) was the primary endpoint. The FFIS score...
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