Uncovering Mechanistic Determinants of Host Phenotypes Using Microbial Systems Biology.

Abstract excerpt

Host phenotypes are caused by a multitude of interacting factors, including but not limited to the microbiome. The advent of high-throughput sequencing technology revolutionized our ability to characterize host-associated microbial communities. Early microbiome profiling studies often focused on strategies such as 16S rRNA gene amplicon sequencing to assess the relative abundance of host-associated microbiota....

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