Article
Substance Use Disorders Are Associated With Increased Long-Term Risks of Gastroesophageal Reflux Disease Phenotypes: A Global Propensity-Matched Cohort Study.
Neurogastroenterology and motility - 1 May 2026
Sun Yan, Veccia Donovan, Liu Benjamin, Tarabichi Yasir, Wei Ruhan, Song Gengqing, Fass Ronnie
Abstract excerpt
BACKGROUND: Substance use disorders (SUDs) may alter esophagogastric function, yet their long-term impact on gastroesophageal reflux disease (GERD) phenotypes and complications has remained unclear. The aim of this study is to evaluate whether SUDs are associated with increased risk of GERD, non-erosive reflux disease (NERD), erosive esophagitis (EE), Barrett's esophagus (BE), and GERD-related complications....
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