Article
[Expert consensus on adverse events management of highly selective RET-TKIs (2026 edition)].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 Jun 2026
Abstract excerpt
The rearranged during transfection (RET) gene is a proto-oncogene encoding a receptor tyrosine kinase. RET gene alterations are driver events in various tumors. Pralsetinib and selpercatinib are novel, highly selective RET tyrosine kinase inhibitors (RET-TKIs). They are recommended as priority therapeutic options for RET fusion-positive non-small cell lung cancer (NSCLC) in the Chinese Society of Clinical...
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