Fecal microbiome of patients with ulcerative colitis reflects their phenotype and inflammatory level.

doi:10.1038/s41598-026-44895-6

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Article

Fecal microbiome of patients with ulcerative colitis reflects their phenotype and inflammatory level.

Scientific reports - 19 May 2026

Maziers Nicolas, Le Chatelier Emmanuelle, Plaza Oñate Florian, Fromentin Sébastien, Thirion Florence, Pons Nicolas, Borruel Natalia, Casellas Francesc, Torrejon Antonio, Robles-Alonso Virginia, Manichanh Chaysavanh, Varela Encarna, Derrien Muriel, Veiga Patrick, Oozeer Raish, Sunagawa Shinichi, Lombard Vincent, Terrapon Nicolas, Henrissat Bernard, Guarner Francisco, Ehrlich S Dusko

Abstract excerpt

Inflammatory bowel diseases affect ever-increasing numbers of individuals worldwide. Alterations of the intestinal microbiome were reported for Crohn's disease and at relapse in Ulcerative Colitis (UC); they were not clearly detected in UC at remission. Here we report the characterization of the microbiome by quantitative metagenomics in a cohort of 121 individuals, composed of 65 UC adult patients in remission...

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Identifiers

PMID: 42156414
DOI: 10.1038/s41598-026-44895-6
PMCID: PMC13469089

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