Article
Detection of Parental Reciprocal Translocations via Inter-Chromosomal Linkage Disequilibrium in Offspring Genotypes.
Animal genetics - 1 Jun 2026
Boshove Anne, Bouwman Aniek C, Pook Torsten, Derks Martijn F L
Abstract excerpt
Reciprocal translocations (RTs) are among the most common structural chromosomal abnormalities observed in both humans and livestock, characterized by the exchange of DNA segments between two non-homologous chromosomes and associated with reduced fertility in carriers. Live-born offspring of RT-carriers have an approximately 50% chance of inheriting a balanced translocation, increasing the linkage disequilibrium...
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