Article
Tezepelumab in real-world US patients with severe asthma across phenotypes and underrepresented populations: the phase 4 PASSAGE study.
American journal of respiratory and critical care medicine - 1 Sept 2026
Lugogo Njira L, Akuthota Praveen, Sumino Kaharu, Burnette Autumn F, Mathur Sameer K, Lindsley Andrew W, Llanos Jean-Pierre, Marchese Claudio, Ambrose Christopher S, Emmanuel Benjamin
Abstract excerpt
RATIONALE: Clinical trials of severe asthma therapies often exclude or underrepresent key patient populations. OBJECTIVES: To evaluate the effectiveness and safety of tezepelumab in a diverse, real-world US population with severe, uncontrolled asthma (SUA). METHODS: PASSAGE was a phase 4, multicenter, single-arm, open-label, 12-month study enrolling patients with SUA (≥12 years old), including different...
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