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Clinical phenotypes of severe dengue and their temporal evolution during a Reunion Island epidemic: a retrospective cohort study.

Travel medicine and infectious disease - 1 Jan 2026

Allyn Jerome, Vidal Charles, Soupin-Coulin Quentin, Doucet Willelm, Devineau Marjolaine, Blanc Zoé, Frumence Etienne, Ferdynus Cyril, Caron Margot, Allou Nicolas

Abstract excerpt

BACKGROUND: The clinical heterogeneity of severe dengue suggests the existence of distinct organ dysfunction patterns. This exploratory study aimed to describe these patterns at ICU admission in Reunion Island (2017-2022) and to analyze how they evolved over time throughout the epidemic. METHODS: We performed a multiple correspondence analysis followed by ascending hierarchical clustering, using organ failure...

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PMID: 42134483
DOI: 10.1016/j.tmaid.2026.102987

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