Article
The genetic association of miR-34a-5p rs72631823 with the susceptibility to obstetric antiphospholipid syndrome.
BMC women's health - 13 May 2026
Wang Junhuan, Huang Yingxuan, Wang Ronghua, Li Chen, Lei Lingyan, Zhang Yue, Zhao Xiangzhuo, Qi Xuan, Li Mingxia
Abstract excerpt
BACKGROUND: Obstetric antiphospholipid syndrome (OAPS) is a complex autoimmune disorder affecting women. miR-34a-5p is upregulated in APS patients, yet the role of functional pre-miR-34a rs72631823 polymorphism in OAPS susceptibility and outcomes remains unexplored. METHODS: This case-control study collected 182 OAPS patients and 188 matched healthy pregnant women (confirmed aPL-negative). The rs72631823...
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