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Article

Circulating microRNA Profiles as Diagnostic Tools for High-Grade Cervical Lesions and HPV Genotype Stratification.

Cells - 6 May 2026

Tamenang Annika, Vohl Vanessa, Schwartz Charlotte, Kropidlowski Jolanthe, Jaeger Anna, Hintelmann Katharina, Vettorazzi Eik, Goy Yvonne, Petersen Cordula, Peine Sven, Pantel Klaus, Schmalfeldt Barbara, Woelber Linn, Wikman Harriet, Effenberger Katharina

Abstract excerpt

Persistent high-risk human papillomavirus (hr-HPV) infection drives cervical carcinogenesis, yet improved molecular biomarkers are needed to define high-risk groups. Circulating microRNAs (miRNAs), stable in blood and involved in carcinogenic pathways, represent promising liquid biopsy biomarkers. This study assessed five miRNAs for distinguishing high-grade squamous cell intraepithelial lesions (HSILs) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42121949
DOI: 10.3390/cells15090849
PMCID: PMC13162731

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