A standardized workflow for typing S. marcescens outbreaks using FT-IR spectroscopy.

doi:10.1007/s10096-026-05448-x

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Article

A standardized workflow for typing S. marcescens outbreaks using FT-IR spectroscopy.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Sept 2026

Passaris Ioannis, Van Goethem Sam, Crombé Florence, Hamerlinck Hannelore, Desmet Stefanie, Naesens Reinout, Willems Philippe, De Geyter Deborah, Leroux-Roels Isabel, Glupczynski Youri, Malhotra-Kumar Surbhi, Goossens Herman, Ceyssens Pieter-Jan

Abstract excerpt

PURPOSE: In this study, we evaluated the performance of FT-IR spectroscopy for clonality assessment of Serratia marcescens by comparing its clustering output to that of whole-genome sequencing (WGS), using core genome single nucleotide polymorphism (cgSNP) analysis as reference. METHODS: A genetically diverse set of Serratia marcescens clinical isolates was collected from different hospitals in Belgium and...

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Topics

Serratia marcescens
Humans
Spectroscopy, Fourier Transform Infrared
Disease Outbreaks

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Workflow

Serratia Infections

Whole Genome Sequencing

Bacterial Typing Techniques

Belgium

Polymorphism, Single Nucleotide

Reproducibility of Results

Cluster Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 42118238
DOI: 10.1007/s10096-026-05448-x
PMCID: PMC13593706

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