Vaginal Escherichia coli infection impairs ovarian homeostasis: phenotypic characterization and mechanistic insights.

Abstract excerpt

Premature ovarian insufficiency (POI), a condition characterized by the loss of ovarian function before the age of 40, has emerged as a critical contributor to declining global fertility rates and the increasing prevalence of female infertility. Growing epidemiological evidence suggests that reproductive tract infections may represent a previously underappreciated risk factor for POI development, although the...

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