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Familial risks in prostate cancer between brothers and half-brothers as clues to germline genetic and environmental causes.

Familial cancer - 11 May 2026

Hemminki Kari, Zitricky Frantisek, Sundquist Kristina, Sundquist Jan, Försti Asta, Hemminki Akseli, Hemminki Otto

Abstract excerpt

Swedish family and cancer data constitute the largest source on familial cancer in the world. We analyze here familial risks in prostate cancer (PC) with focus on multiple affected brothers and comparation of full-brothers to maternal and paternal half-brothers. Age-specific incidence and standardized incidence ratios (SIRs) were calculated for PC in brothers. Curves for relative risk (RR) by diagnostic age were...

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Identifiers

PMID: 42113346
DOI: 10.1007/s10689-026-00562-3
PMCID: PMC13161322

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PC

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