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Article

Noninvasive Risk Stratification Based on Renal Tubular Injury Phenotypes: A Deep Learning Study for Predicting Vesicoureteral Reflux in Children.

Journal of cellular and molecular medicine - 1 May 2026

Lin Hongzhou, Cui Zeyu, Zhang Zhantian, Luo Yifan, Shuai Jianwei, Zhao Kai, Zhou Yunlong, Wang Dexuan

Abstract excerpt

Vesicoureteral reflux (VUR) can cause retrograde urine flow under voiding pressure, facilitating ascending bacterial colonisation and recurrent inflammatory responses. These processes trigger a cascade of cellular and molecular events-innate immune activation, pro-inflammatory cytokine release, oxidative stress, apoptosis and extracellular matrix deposition-thereby promoting tubulointerstitial remodelling and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42108518
DOI: 10.1111/jcmm.71172
PMCID: PMC13158276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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