An integrated cardiometabolic genetic testing program in a predominantly Hispanic population within a community setting.

doi:10.1016/j.gim.2026.102595

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An integrated cardiometabolic genetic testing program in a predominantly Hispanic population within a community setting.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jul 2026

Yuan Bo, Abushamat Layla A, Pereira Stacey, Mulukutla Surya Narayan, Tietz Grace E, Venner Eric, Kalla Sara E, Lee Breanna, Muzny Donna, Metcalf Ginger, Murugan Mullai, Elsea Sarah H, Kadirvel Senkottuvelan, Li Lele, Stephen Joshi, Xu Shengfeng, Yi Victoria, Sulit Monica, Kovar Christie L, Walker Kimberly, Gingras Marie-Claude, Hu Jianhong, Yan Fei, Gerber Taeko, Korchina Viktoriya, Fordis C Michael, Gaba Ruchi, Changlani Mahesh, Silberman Herschl, Smith Hadley Stevens, Eng Christine M, Posey Jennifer E, Medina Clarisa, Treviño Lisa R, Ballantyne Christie M, Gibbs Richard A, Balasubramanyam Ashok

Abstract excerpt

PURPOSE: This study aimed to apply cardiometabolic genetic testing in a community setting with a predominantly Hispanic population and assess feasibility and perspectives toward genetic testing. METHODS: A genome-sequencing-based genetic panel for cardiometabolic disorders (177 genes related to monogenic conditions, 2 LPA risk alleles, 2 pharmacogenomic loci, and ancestry-adjusted polygenic risk scores for type 2...

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PMID: 42104850
DOI: 10.1016/j.gim.2026.102595
PMCID: PMC13430617

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