Article
Multi-center-validated machine learning model for cervical cancer based on human papillomavirus genotyping results.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jun 2026
Chen Ziren, Zeng Yihui, Luo Lingxiao, Li Juan, Zheng Liangkai, Xie Yan, Xiao Jingjing, Zhang Lu, Zhang Qi, Sun Yixin, Sun Xiaoyi, Sui Long, Tao Xiang, Cong Qing
Abstract excerpt
OBJECTIVE: Cervical cancer remains a leading cause of gynecologic cancer-related mortality worldwide, with human papillomavirus (HPV) testing being a key screening tool. However, current guidelines often categorize high-risk HPV types broadly, overlooking their varying oncogenic potentials. This study aimed to develop and validate a machine learning model to predict cervical intra-epithelial neoplasia grade (CIN)...
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