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Article

Intractable epilepsy before and/or after awake functional mapping-based surgery for IDH-mutant grade 2 glioma: a consecutive series of 105 patients.

Journal of neurosurgery - 1 Sept 2026

Ng Sam, Duffau Hugues

Abstract excerpt

OBJECTIVE: Awake resection in grade 2 glioma (G2G) improves quality of life (QOL) and overall survival (OS). Nonetheless, epilepsy occurs frequently in this context and can impair QOL, especially when the disorder is pharmacoresistant. Herein, the goal was to study patients with intractable epilepsy (IE) before and/or after surgery for a G2G. METHODS: Patients who underwent awake functional mapping-based...

Read the complete abstract on PubMed

Topics

Humans
Female
Brain Neoplasms
Male
Glioma
Adult
Retrospective Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Brain Mapping

Middle Aged

Wakefulness

Drug Resistant Epilepsy

Young Adult

Isocitrate Dehydrogenase

Treatment Outcome

Neurosurgical Procedures

Mutation

Adolescent

Quality of Life

Source

Identifiers

PMID: 42102408
DOI: 10.3171/2025.12.JNS251916

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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