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Article

Prognostic Factors and Oncofunctional Outcomes of WHO 2021-Classified Insular Gliomas Undergoing Awake Brain Mapping.

World neurosurgery - 1 Sept 2026

Motomura Kazuya, Mitsuya Koichi, Kibe Yuji, Kondo Masaki, Terano Mizuki, Ohka Fumiharu, Saito Ryuta

Abstract excerpt

OBJECTIVE: This study aimed to evaluate prognostic factors and oncofunctional outcomes, including neurological and neurocognitive preservation, in patients with World Health Organization 2021-classified insular lower-grade gliomas and glioblastoma who underwent awake brain mapping. METHODS: We retrospectively analyzed 36 consecutive patients with insular glioma, including LrGGs and GBM, who underwent awake...

Read the complete abstract on PubMed

Topics

Humans
Brain Neoplasms
Glioma
Female
Brain Mapping
Male
Prognosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Retrospective Studies

Middle Aged

Wakefulness

Isocitrate Dehydrogenase

Insular Cortex

Treatment Outcome

Aged

Mutation

Source

Identifiers

PMID: 42498227
DOI: 10.1016/j.wneu.2026.125210

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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