Article
Isolated Anaplastic Transformation of Tall Cell Papillary Thyroid Carcinoma in Metastatic Lymph Nodes With Extremely Rare Co-Occurrence of BRAF p.V600E and KRAS p.G12R Mutations: A Unique Case.
Diagnostic cytopathology - 1 Aug 2026
Chia Alicia Ming Xi, Go Lih Khuang, Teo Hui Lin, Gan Jereme Yi Jin, Bundele Manish Mahadeorao
Abstract excerpt
We report a case of a 57-year-old male with anaplastic transformation of papillary thyroid carcinoma (PTC) in metastatic lymph nodes. This case presents as a pitfall due to squamous differentiation in anaplastic thyroid carcinoma, which was initially misinterpreted as metastatic squamous cell carcinoma on fine needle aspiration (FNA) of the lymph node in the neck. Subsequent surgical resection reveals a unique...
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