Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual recognition of structurally unrelated mildew effectors underlies the broad-spectrum resistance of Pm3e in wheat.

Nature communications - 2 May 2026

Kunz Lukas, Bernasconi Zoe, Heuberger Matthias, Isaksson Jonatan, Sotiropoulos Alexandros G, Stirnemann Ursin, Jigisha Jigisha, Menardo Fabrizio, Wicker Thomas, Müller Marion C, Keller Beat

Abstract excerpt

Broad-spectrum resistance genes are highly valuable for sustainable crop protection, yet the molecular basis of their activity is often unknown. The Pm3 allelic series in wheat encodes NLR receptors that recognize avirulence (AVR) effectors of wheat powdery mildew. Here, we show that near-identical Pm3 alleles vary greatly in resistance efficacy and broadness against a global mildew isolate collection and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Ascomycota

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Resistance

Share to NLR Proteins

Share to Plant Diseases

Share to Plant Proteins

Share to Triticum

Source

Open in PubMed Open full text

Identifiers

PMID: 42069721
DOI: 10.1038/s41467-026-72199-w
PMCID: PMC13342611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dual recognition of structurally unrelated mildew effectors underlies the broad-spectrum resistance of Pm3e in wheat.PMID 42069721Read ↗

Single residues in the LRR domain of the wheat PM3A immune receptor can control the strength and the spectrum of the immune response.Semantic proximity Read ↗

Distinct domains of the AVRPM3A2/F2 avirulence protein from wheat powdery mildew are involved in immune receptor recognition and putative effector function.Semantic proximity Read ↗

Mutagenesis of Wheat Powdery Mildew Reveals a Single Gene Controlling Both NLR and Tandem Kinase-Mediated Immunity.Semantic proximity Read ↗

Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles.Semantic proximity Read ↗

Identification of specificity-defining amino acids of the wheat immune receptor Pm2 and powdery mildew effector AvrPm2.Semantic proximity Read ↗

Natural variation in Avr3D1 from Zymoseptoria sp. contributes to quantitative gene-for-gene resistance and to host specificity.Semantic proximity Read ↗

Allelic barley MLA immune receptors recognize sequence-unrelated avirulence effectors of the powdery mildew pathogen.Semantic proximity Read ↗

Resurrection of the Plant Immune Receptor Sr50 to Overcome Pathogen Immune EvasionSemantic proximity Read ↗

Wheat Pm55 alleles exhibit distinct interactions with an inhibitor to cause different powdery mildew resistance.Semantic proximity Read ↗

Rye Pm8 and wheat Pm3 are orthologous genes and show evolutionary conservation of resistance function against powdery mildew.Semantic proximity Read ↗

The wheat NLR protein PM3b localizes to endoplasmic reticulum-plasma membrane contact sites and interacts with AVRPM3 <sup>b2/c2</sup> through its LRR domainSemantic proximity Read ↗

The leucine-rich repeats in allelic barley MLA immune receptors define specificity towards sequence-unrelated powdery mildew avirulence effectors with a predicted common RNase-like fold.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.