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Article

Genetic risk score as a predictor of gestational diabetes in Central European Caucasians.

Scientific reports - 29 Apr 2026

Hubáček Jaroslav A, Galuška David, Krejčířová Beáta, Bartáková Vendula, Chalásová Katarína, Pácal Lukáš, Lánská Věra, Janků Petr, Ťápalová Veronika, Kaňková Kateřina

Abstract excerpt

Gestational diabetes mellitus (GDM) is a common complication of pregnancy associated with perinatal complications and increased future risk of T2DM. GDM has a polygenic background partly overlapping with T2DM, and using a genetic risk score (GRS) that captures complex genetics may improve early detection of individuals at risk. SNPs previously associated with T2DM in the Czech population (21 loci) have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42056237
DOI: 10.1038/s41598-026-49602-z
PMCID: PMC13319762

Genes

MTNR1B
NOTCH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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