Article
Arabidopsis TMPIT/TMEM120/NET29 homologs are required for cell survival, Golgi morphology, and metabolic fluxes of very long-chain fatty acids to waxes and sphingolipids.
Plant physiology and biochemistry : PPB - 1 May 2026
Chen Jie, Yang Xinxing, Lou Siying, Ma Yuan, Huang Minhua, Ma Lingxing, Han Ning, Bian Hongwu, Tu Min, Qiu Ting, Yang Yanjun, Yang Wanxi, Wang Junhui
Abstract excerpt
The TMPIT/TMEM120/NET29 family of transmembrane proteins is conserved in eukaryotes, but its functions are controversial in mammals and have not been reported in plants. Structurally, these proteins were supposed to contain a coenzyme A (CoA)-binding motif and exhibit high similarity to that of ELOVL7, an enzyme involved in VLCFA (very long-chain fatty acid) elongation. Here, we report that due to functional...
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