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Emergence and Rapid Spread of a New Reassortant High Pathogenicity H5N1 Clade 2.3.4.4b Avian Influenza Virus in Nigeria.

Influenza and other respiratory viruses - 1 May 2026

Meseko Clement, Zecchin Bianca, Go-Maro Emilie Wolali, Dianati Marta, Mkpuma Nicodemus, Inuwa Bitrus, Bakam Judith, Olawuyi Kayode, Gado Dorcas, Giussani Edoardo, Fusaro Alice, Bortolami Alessio, Palumbo Elisa, Terregino Calogero, Monne Isabella

Abstract excerpt

Over the past two decades, West Africa has experienced recurrent incursions of Goose/Guangdong-lineage highly pathogenic avian influenza (HPAI) A(H5N1), with Nigeria as a hotspot for repeated introductions and sustained circulation. Since 2021, European-origin clade 2.3.4.4b H5Nx genotypes, particularly EA-2020-C, have predominated in regional poultry. Here, we report the emergence and rapid spread in Nigeria,...

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PMID: 42046457
DOI: 10.1111/irv.70260
PMCID: PMC13121905

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