Article
A high prevalence of hepatitis B virus strains sharing a single S gene variant in Pakistan.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2026
Thai Hong, Almas Iqra, Xia Guo-Liang, Lin Yulin, Sims Seth, Longmire Atkinson, Arthur Leonard, Idrees Muhammad, Afzal Samia, Khudyakov Yury
Abstract excerpt
HBV infection is a significant public health problem in Pakistan. However, little is known about HBV genetic heterogeneity in the country. Here, we study inter- and intra-host heterogeneity of the HBV S gene. HBV S gene was sequenced using Sanger and Next-Generation Sequencing (NGS) technologies from patients (n = 155) in two provinces. HBV genotype D (HBV/D) was found prevalent (98.7%). Phylogenetic analysis of...
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