Article
Influenza household transmission and genomic diversity in the United States: A prospective cohort study, 2022-2024.
The Journal of infection - 1 May 2026
Cox Sarah N, Bennett Julia C, Casto Amanda M, Hoffman Katherine L, Frivold Collrane, Carone Marco, Acker Zack, Babu Tara M, Boisvert Cassandra L, Ehmen Brenna, Englund Janet A, Grindstaff Sally, Han Peter, Hatchie Tara L, Kuntz Jennifer L, Lockwood Christina M, McCaffrey Kathryn M, Mularski Richard A, Regelbrugge Lani, Reich Sacha, Schmidt Mark A, Smith Ning, Starita Lea, Stone Jeremy, Varga Alexandra, Weil Ana A, Naleway Allison L, Chu Helen Y
Abstract excerpt
OBJECTIVES: To analyze the extent and risk factors of household influenza transmission using molecular testing and viral genomes. METHODS: In a community-based cohort in the United States during 2022-2024, participants self-collected weekly nasal swabs. Swabs were tested for influenza by RT-PCR; genomic sequencing was performed. Index cases had the first influenza detection within households. Factors associated...
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